Housekeeping employees of the medical center were recruited for a federally funded study of blood pressure, blood count levels, infectious disease history, and job stress. the interviews and blood tests were conducted in a private location not affiliated with the study center. follow-up interviews were conducted in the same location. the study coordinator stopped at the cafeteria on her way back to the study office after the second study visit for the last three study subjects and lost the three file folders. records of one subject indicated he had a history of a sexually transmitted disease and another had recently been treated for tuberculosis. the subjects were notified of the loss. following this event, the irb approved a protocol change requiring that all records be transmitted electronically to the study office using the medical center’s secure network. which of the follwoing should be reason:
(a)-this is an unanticipated problem and not an adverse event.
(b)-this is an anticipated problem and not an adverse event.
(c)- this is an unanticipated problem and an adverse event.
(d)- none of these

 c)This is an unanticipated problem and not an adverse event.

Explanation: The situation mentioned in the question is regarding the lost record of the last three studies that is blood study, history of infectious disease and stress of job. Therefore, important data is lost in this case.

IRB is giving the order of changing the protocol and sending the record electronically because they work for welfare and protecting the rights and information that collected in a research study .By sending data through secure network , losing information case cannot happen and it can remain secure.

They gave this order because the case is an unexpected issue that can result in the harmful effect..Other options are incorrect because  the problem is not expected so it cannot be anticipated and it can possibly have severe effects.Thus,the correct option is option(c).

d would be your answer

    however, coronary heart disease , or chd, is actually a result of coronary artery disease, or cad, said edward a. fisher, m.d., ph.d., m.p.h., an american heart association volunteer who is the leon h. charney professor of cardiovascular medicine and also of the marc and ruti bell vascular biology and disease program at the nyu school of medicine.

  with coronary artery disease, plaque first grows within the walls of the coronary arteries until the blood flow to the heart’s muscle is limited. view an illustration of coronary arteries. this is also called ischemia. it may be chronic, narrowing of the coronary artery over time and limiting of the blood supply to part of the muscle. or it can be acute, resulting from a sudden rupture of a plaque and formation of a thrombus or blood clot.

    the traditional risk factors for coronary artery disease are high ldl cholesterol, low hdl cholesterol, high blood pressure, family history, diabetes, smoking, being post-menopausal for women and being older than 45 for men, according to fisher. obesity may also be a risk factor.

    “coronary artery disease begins in childhood, so that by the teenage years, there is evidence that plaques that will stay with us for life are formed in most people,” said fisher, who is former editor of the american heart association journal, atvb. “preventive measures instituted early are thought to have greater lifetime benefits. healthy lifestyles will delay the progression of cad, and there is hope that cad can be regressed before it causes chd.”

  living a healthy lifestyle that incorporates good nutrition, weight management and getting plenty of physical activity can play a big role in avoiding cad.

    “coronary artery disease is preventable,” agreed johnny lee, m.d., president of new york heart associates, and an american heart association volunteer. “typical warning signs are chest pain, shortness of breath, palpitations and even fatigue.” if you feel any of these symptoms, don’t delay — call 9-1-1.