Chronic myelogenous leukemia (cml) is a type of cancer that is caused by a specific chromosomal alteration that leads to the inappropriate expression of a kinase called abl. kinases are enzymes that put phosphate groups onto macromolecules such as proteins. a drug used to treat cml, imatinib, binds to the active site of abl kinase. why does this drug work to treat this type of cancer?

[120 total points] (public health) in one of the largest human experiments ever conducted, in 1954 a randomized controlled trial was run to see whether a vaccine developed by a doctor named jonas salk was effective in preventing paralytic polio. a total of 401,974 children (ages 6–9), chosen to be representative of those who might be susceptible to the disease, were randomized to two groups: 200,745 children (the control group c) were injected with a harmless saline solution (a placebo) and the other 201,229 children (the treatment group t) were injected with salk’s vaccine.what was the point of giving saline solution to the children who didn’t get the vaccine? explain briefly.

Choose thyroid, parathyroid, or the adrenal gland and choose one disease affecting this part of the en-docrine system.

Life expectancy in the united states is (76.4 for men and 81.1 for women). life expectancy is not the same as healthy life expectancy. healthy life expectancy is the number of years a person is expected to live in this number is obtained by subtracting years spent in poor health from overall life expectancy. the world health organization (who) calculates healthy life expectancy in 194 countries. the united states ranks twenty-ninth in the world using this measurement, with an average of of healthy life expectancy. singapore ranks number one (76 years), and japan is number two (75 years).