What client characteristic may contraindicate the use of tramadol for the treatment of a clientâs pain following traumatic injuries?

Tramadol should not be used in people who:

Explanation:

  Tramadol is an opioid painkiller that acts on the central nervous system and is indicated for the relief of pain of moderate to severe intensity.  It acts similarly to endorphins, which are natural neurotransmitters related to pain and well-being. Endorphins act by binding to brain opioid receptors by decreasing pain messages that reach the central nervous system.  Like other opioids, tramadol also exerts its analgesic effect by binding these opioid μ receptors, acting as if they were endorphins and blocking the transmission of electrical impulses of pain by the nervous system. When μ opioid receptors are activated, the brain is less able to recognize pain signals sent by the body.

   The prescription of tramadol is contraindicated in the following situations:

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explanation: