Abnormal chromosomes are frequently found in malignant tumors. Errors such as translocations may place a gene in close proximity to different control regions. Which events might then occur to make the cancer worse?

Uncontrolled proliferation of cells.

Explanation:

Mutations that accumulates overtime in chromosomes of these cells are found in malignant tumours. When such errors occurs placing a gene in close proximity to different control region, these errors may affect the different control region and cause them to lose their functions. Most of them function to regulate the rate at which the cell divides but when these errors occur, they lose their function and the cells divides uncontrollably making the cancer worse and even to metastasis.