Decreasing grades in school using illegal drugs
inability to control anger
sudden mood swings
hope of impressing coach
disappointment in not making the team

In multiple sclerosis, the immune system destroys the substance that coats and protects nerve fibers in the brain and spinal cord. this causes inflammation and injury to the nerves, and the axons don't conduct impulses as well.

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for

A41-year-old man comes to the clinic complaining of a chronic cough over the past 4 months, which has now been accompanied by haemoptysis. he denies smoking or any past medical history. on physical examination, his head and neck examination is normal. his lungs have diffuse bilateral rales. cardiac examination is normal. laboratory findings reveal na 142 meq/l, k 4.2 meq/l, cl 110 meq/l, hco3 24 meq/l, bun (blood urea nitrogen) 39 mg/dl, creatinine 2.9 mg/dl. urinalysis reveals microscopic haematuria and 4+ proteinuria. which of the following serologic blood tests would most confirm the suspected diagnosis? - anti-glomerular basement membrane antibodies- anti-mitochondrial antibodies- anti-neutrophilic antibodies- anti-parietal cell antibodies- anti-smooth muscle antibodies