The field of biotechnology R&D is constantly evolving and improving. Think about how this field must have looked 20 years ago, before certain trends and advancements. Identify and write about two or three trends and technologies that have made a difference to the biotechnology R&D field over the past two decades. Write two or three sentences about how each of these trends and technologies has improved biotechnology R&D. Then, think about ways in which biotechnology R&D might improve even further over the next ten years. Write your response in two or three short paragraphs. You can use the Internet to conduct research.

A92-year-old man with a 45-year history of chronic obstructive pulmonary disease is intubated in the icu because of a bout of viral pneumonia that fails to improve after 72 hours of antibiotics. although the inspired fraction of oxygen is 100%, the patient's po2 remains at 57 mmhg. positive-end expiratory pressure (peep) is added to allow the inspired fraction of oxygen. twelve hours after the introduction of peep the patient suddenly become hypotensive. at the same time, his oxygen saturation drops from 92% to 61%. on physical examination, his bp is 80/50 mmhg and his pulse is 124/min. he has distended neck veins and distant heart sounds. which of the following would also most likely be seen on this patient's physical examination? - absence of breath sounds in the right hemithorax- high amplitude carotid artery upstroke- a pleural friction rub- pulsus alternans- splenomegaly