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In this model, what do p, s, and a bases represent?

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Which of the following statements concerning cancer and mutations is correct? a: cancer can only occur with a mutation in a somatic cell. b: usually, multiple mutations are required in different genes to cause cancer. c: none of the other answer options is correct. d: cancer can only occur with a mutation in a germ cell. e: usually, a single mutation is all that is required to cause cancer.