Tay sachs disease is caused by a mutation of one nucleotide for a protein that disrupts the activity of an enzyme in the brain. this leads to a toxic level of a substance to build up in neurons in the brain and spinal cord, leading to severe brain damage and eventually death. why do you think that the change in one nucleotide can cause tay sachs disease to be fatal, whereas the change in one nucleotide causes sickle cell disease, a disease in which a person can lead a functional life?

In this model, what do p, s, and a bases represent?

A24-year-old g4p2 woman at 34 weeks gestation complains of a cough and whitish sputum for the last three days. she reports that everyone in the family has been sick. she reports a high fever last night up to 102°f (38.9°c). she denies chest pain. she has a history of asthma with no previous intubations. she uses an albuterol inhaler, although she has not used it this week. vital signs are: temperature 98.6°f (37°c); respiratory rate 16/minute; pulse 94 beats/minute; blood pressure 114/78; peak expiratory flow rate 430 l/min (baseline documented in the outpatient chart = 425 l/min). on physical examination, pharyngeal mucosa is erythematous and injected. lungs are clear to auscultation. white blood cell count 8,700 mcl; arterial blood gases on room air (normal ranges in parentheses): ph 7.44 (7.36–7.44); po2 103 mm hg (> 100); pco2 26 mm hg (28–32); hco3 19 mm hg (22–26). chest x-ray is normal. what is the correct interpretation of this arterial blood gas?

Effective antiviral drugs are usually associated with which of the following properties? a) interference with viral replicationb) prevention of the host from becoming infectedc) removal of viral proteinsd) removal of viral mrnas