Sophia’s doctor suspects she’s been using marijuana for a long period of time. Which set of symptoms best describes what Sophia’s doctor observes? Sophia exhibits impaired memory and learning.
Sophia is hoarse and malnourished with nosebleeds.
Sophia complains of itching, nausea, and a racing heart.
Sophia has severe dental problems, anxiety, and a sleep disorder.

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for