What is one manner in which viruses are distinguished from prokaryotes?

Both viruses and prokaryotes need essential macromolecules (e.g. proteins, nucleic acids) to propagate, but only prokaryotes are able to use these macromolecules themselves when they replicate/divide. Viruses are obligate intracellular parasites, meaning they require a host to replicate; they do not have the molecular machinery to independently multiply.

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