Would it be more effective to stress reduction of drug use rather than a complete prohibition of drug use?

It would be more effective.

Let's play out a scenario of complete prohibition.

Complete prohibition --> Drug users retaliate --> Deaths due to instant withdrawal --> Smuggling operations skyrocket due to constant need for drugs

To stress reduction instead of banning it would allow users the freedom to end it by themselves, slowly and slowly.

There is a lot of things if u give me the list i can

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