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Spherocytosis is an inherited blood disease in which the erythrocytes (red blood cells) are spherical instead of biconcave. this condition is inherited in a dominant fashion, with sph- dominant to sph+. in people with spherocytosis, the spleen "reads" the spherical red blood cells as defective, and it removes them from the bloodstream, leading to anemia. the spleen in different people removes the spherical erythrocytes with different efficiencies. some people with spherical erythrocytes suffer severe anemia and some mild anemia, yet others have spleens that function so poorly there are no symptoms of anemia at all. when 2400 people with the genotype sph- sph+ were examined, it was found that 2250 had anemia of varying severity, but 150 had no symptoms. does this description of people with spherocytosis represent incomplete penetrance, variable expressivity, or both? explain your answer. (3 points)

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Poliovirus is an rna virus of the picornavirus group, which uses its rna as mrna. at its 5' end, the rna genome has a viral protein (vpg) instead of a cap. this is followed by anontranslated leader sequence, and then a single long protein-coding region (~7000 nucleotides), followed by a poly-a tail. observations were made that used radioactive amino acid analogues. short period use of the radioactive amino acids result in labeling of only very long proteins, while longer periods of labeling result in several different short polypeptides. what conclusion is most consistent with the results of the radioactive labeling experiment? a) host cell ribosomes only translate the viral code into short polypeptides.b) the rna is only translated into a single long polypeptide, which is then cleaved into shorter ones.c) the rna is translated into short polypeptides, which are subsequently assembled into large ones.d) the large radioactive polypeptides are coded by the host, whereas the short ones are coded for by the virus.