What is the first sign of a syphilis infection? a)small clear or yellowish blisters
b)a dime-sized, painless sore call a chancre
c)painful urination
d)sore throat, fever, muscle pain, rash

B) a dime-sized, painless slre call a chancre

Depression is lifelong, though you can get medication to with it. the difference between sadness and depression is that sadness lasts a little bit, depression last a long time and it goes on and off. people usually get depression through experiences they have been through, or genetics.