What is substance abuse? A. When someone becomes addicted to a drug
B. When someone takes a drug just for fun
C. When someone experiences withdrawal symptoms
D. When someone becomes irritable without their favorite drug

A would probably be the best answer for this question.

Explanation:

Substance abuse is when somebody takes too much of physcioactive drugs which can result in physical or mental instability or harm.

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A

Using both words in the sentence, you will know this:

substance: commonly a drug, or liquor

abuse: doing it excessively.

So, what you learn at the end: doing a drug/liquor excessively. The answer choice that makes the most sense here in a negative tone is A.

it may have problems procreating.