Why might people curse or express loathing for those citizens who support the constitution

Those who supported the Constitution and a stronger national republic were known as Federalists On the other hand those who opposed the Constitution in favor of small localized government were known as Anti-Federalists. Both  were concerned with the preservation of liberty, however, they disagreed whether a strong national government would preserve or eventually destroy the liberty. So you could say that those who supported the Constitution were perceived as a threath to freedom and liberty.

small european communities with shared traditions consolidated into large new states (apex)

islamic religious leaders have traditionally been people who, as part of the clerisy, mosque, or government, performed a prominent role within their community or nation. however, in the modern contexts of muslims minorities in non-muslim countries as well as secularised muslim states like turkey, indonesia and bangladesh, religious leadership may take a variety of non-formal shapes.

compared to religious leaders/clerics of the other abrahamic faiths, islamic clergy are said to resemble rabbis and not priests. unlike catholic priests they do not "serve as intermediaries between mankind and god",[1] have "process of ordination",[2] or "sacramental functions",[1] but instead serve as "exemplars, teachers, judges, and community leaders," providing religious rules to the pious on "even the most minor and private" matters.[1]