Why did many politicians in the united states oppose the louisiana purchase?

As seems to happen so often in politics, the Federalists opposed the Louisiana Purchase not on principled grounds but because they thought it would hurt them politically. They claimed to oppose the Purchase because it was unconstitutional.

"a shortage of traditional labor created new opportunities in the workplace. a major cause of the internment of japanese americans during world war ii was. racial prejudice. in the early 1940's, the "destroyers-for-military-bases deal" with great britain and the lend-lease act were evidence that the united states."