Most opposition to new deal programs came from
farmers and the unemployed.
supporters of business regulation.
republicans and conservative democrats.
politicians opposed to business competition.

The answer for your following question would be : Republicans and conservative democrats. Most opposition came from the republicans and conservatives because the new deal program seem to really innovative and goes out the way of traditional method in handling the economy, in which they spent more budget to create more jobs

The fact that farmers were paid for destroying crops.