The issue or event that most directly led to american revolution was

Explanation:

the boston tea party and they over pricing thier tea and etc.

harding's opponent in the 1920 election was ohio governor and newspaperman james m. cox, who had won the democratic nomination in a 44-ballot convention battle. harding rejected the progressive ideology of the wilson administration in favor of the laissez-faire approach of the mckinley administration.

i think it’s will be a yes