In the first half of the 1600s, american indians in virginia and maryland most typically?

Defending their territories against English.

Explanation:

In the beginning, the colonies grew to form in the harsh environment with the Native Indians surrounding them. But the peace did not last as the settlers began to increase their colonies which threatened the lands of the native Indians. The whites viewed the Indians as possessors of land. The expropriation attitudes of the whites partially justify as they began to capture the lands of the Indigenous tribes in America.

the answer is b. osage.