Which of the following could affect the human population?

A deadly virus emerges that can pass from human to human.
A hurricane makes landfall on an uninhabited island.
A nuclear war breaks out between two nations.
Immigration to the United States from China increases.

What did anti-federalists believe with regard to the constitution? a. that it would favor slaveholding states over nonslaveholding states b. that it would place too much power in a central government c. that it would put too much power into the hands of individual states d. that it would create an elite upper class that would run the country