Which of the following describes a major pattern of demographic change that characterized almost every early European effort to colonize North America?
A. Unpaid laborers were given no opportunity to eventually win
freedom.
B. Colonial populations were populated largely with married couples.
C. American Indian populations declined in huge numbers.
D. Colonists made little effort to accommodate American Indian
culture.

C. American Indian populations declined in huge numbers.

Explanation:

Primarily, native populations greatly declined because of the diseases that were introduced by the Europeans.

Smallpox was extremely deadly and killed half of the native population, and other diseases like malaria and yellow fever were very deadly as well.

Native populations also declined from the abuse they faced from the Europeans. Many were enslaved under abusive working conditions, leading to them dying from starvation or torture.

Lastly, the natives also died from warfare/conflicts with the Europeans.

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