Florence, Italy, served as the artistic center of the Italian Renaissance. Which region served the same purpose during the Northern Renaissance?

the doctrine of nullification recommended that states living inside the union have the one-sided, inalienable ideal to void any law made by the national government that could be esteemed illegal.

the united states was shaped based on a general agreement among its individual states. hence, it is inferred that under the hypothesis of invalidation, since the states are the establishment of the union, they have the ability to referee and disprove unlawful laws.

after defeating german forces in north africa allied leaders turned their attention to "italy," since this was the location that made the most geographic sense before invading northern europe via france. 

the scientific revolution brought us a renewed understanding of humanity and our place in the universe, new scientific equipment, and new laws as a basis for future scientific discovery.