Hey help ASAP pls

it is the theme

Explanation:

Once you identify a story's plot, setting, characters, and conflict, you can work on finding its theme. The theme is the story's "big idea"

D i believe so cause the plot is the biggest in the story so plot or theme

disease was the number one killer of native peoples. they had had little exposure to the diseases of europe. this led to some villages being almost completely wiped out and some tribes destroyed.