For which of the following major world events was the spread of diseases a negative effect

These are the answer choices for the question:

A. the technological revolution

B. the mapping of the European world

C. the Columbian Exchange

D. the Reformation

Explanation:

The Columbia Exchange started with the arrival of Columbus in the Lesser Antilles in 1492. From this moment on, other Spanish and Portuguese explorerse and conquistadors arrived and explored almost the totality of the American Continent.

Unfortunately for Native Americans, Europeans carried diseases for which they did not have antibodies, diseases like measles, smallpox, or syphillis. These diseases spread quickly to Native Americans, and the vast majority of them (up to 90%) died from them.