45. The excerpt below comes from a sermon given by Governor John Winthrop in 1630. For we must consider that we shall be as a city upon a hill. The eyes of all people are upon us. So that if we shall deal falsely with our God in this work we have undertaken, and so cause Him to withdraw His present help from us, we shall be made a story and a by-word through the world. eradication of smallpox and yellow fever in the New World. c E This excerpt refers to the spread of Catholicism by Spanish conquistadors. O E elimination of Spanish influence on indigenous cultures. establishment of a colony founded for religious purposes.