What political arguments led to the discussion of secession around the time of the civil war?

Slavery

Explanation:

The moment leading up the civil war, the Federal government forced the southerners to end the practice of slavery and exchange it with machines/industries.

The southerners did not want to do it since their economy at that time was heavily reliant on slave labors.

So, the southern states decided to secede. They separated themselves from the Federal government's rule with the intention to form new  independent nations.

um hi i’m new here but i have an opinion i guess. i think we are but when i say war i don’t mean fighting i mean political rallies differing opinions and cultures and ideas and they all clash so hard. not all wars are fought on a battlefield. most are fought in our minds and minds of others. somethings gonna have to change and i honestly think a ‘war’ is the best way to do it. fight it out. stand up for what you believe. it’ll work out. freakin united states of america we’ve got this.