Which pair of statements explain two impacts of the Columbian Exchange?

its many islands, high mountains, and remote peninsulas isolated population centers.

answer; i believe the correct answer is (the willamete valley);

must repent and believe in god.

or the book

journey across time - chapter 10 "the rise of christianity"

necessary and proper clause. the congress shall have power to all laws which shall be necessary and proper for carrying into execution the foregoing powers, and all other powers vested by this constitution in the government of the united states, or in any department or officer thereof.