South Carolina was one of the original thirteen states of the United States. European exploration of the area began in April 1540, with the Hernando de Soto expedition, who unwittingly introduced new Eurasian diseases that decimated the local Native American populations, because they lacked immunity.[1] In 1663, the English Crown granted land to eight proprietors of what became the colony. The first settlers came to the Province of Carolina at the port of Charleston in 1670. They were mostly wealthy planters and their slaves coming from the English Caribbean colony of Barbados. They started to develop their commodity crops of sugar and cotton. North Carolina was officially split off into a separate colony in 1712. Pushing back the Native Americans in the Yamasee War (1715–17), colonists next overthrew the proprietors' rule, seeking more direct representation. In 1719, South Carolina was officially made a crown colony.
In the Stamp Act Crisis of 1765, South Carolina banded together with the other colonies to oppose British taxation and played a major role in resisting Great Britain. It became independent in March 1776 and joined the United States of America.[2][3] The Revolutionary War was bloody and hard-fought in 1780–81, as the British invaded, captured the American army and were finally driven out.
In the early decades, the colony cultivated cotton on plantations of the sea islands and Low Country, along with rice, indigo and some tobacco as commodity crops, all worked by African slaves, most from West Africa. In the 19th century, invention of the cotton gin enabled profitable processing of short-staple cotton, which grew better in the Piedmont than did long-staple cotton. The hilly upland areas, where landowners were generally subsistence farmers with few slaves, were much poorer; a regional conflict between the coastal and inland areas developed in the political system, long dominated by the Low Country planters. With outspoken leaders such as John C. Calhoun, the state vied with Virginia as the dominant political and social force in the South. It fought federal tariffs in the 1830s and demanded that its rights to practice slavery be recognized in newly established territories. With the 1860 election of Republicans under Abraham Lincoln, who vowed to prevent slavery's expansion, the voters demanded secession. In December 1860, the state seceded from the Union, and in February 1861, it joined the new Confederate States of America.

