Conflicting interpretations of the 10th amendment played a major role in what ?

Conflicting interpretations had two major problems, one was that it enabled slavery and other that it enabled nullification. People believed that since slavery was not mentioned in the constitution, the states should have the right to have it if they wanted to. Same for nullification, since new congressional acts were not part of the constitution, states could choose to not implement them because of the 10th amendment.

The answer is c. good luck : )