Lincoln's emancipation proclamation hoped to set all the slaves free, but what was the consequence? not a single slave was freed. hundreds of slaves were freed. all slaves from maryland were freed. only slaves near antietam were freed.

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.

The sumerian empire worshipped a lot of natural aspects like wind. the impact on civilization was people abided by rules to avoid displeasing gods and it created a drive in people to be good. i hope this is what you were looking for, as this question was quite broad.