What kinds of challenges did pioneers heading west in wagon trains face?

What country was the philippines declaring independence from in this proclamation?

1. what was william harvey's discovery about the human body? @ two types of blood flowed through the veins and arteries. b four fluids existed in the body: blood, yellow bile, black bile, and phlegm. © the same blood flowed through the veins and arteries. d ancient ideas of human anatomy and bodily functions were wrong. done

Why did the french settle in new france