How did the unintentional genocide of the Native Americans in the New World lead to race based slavery in the New World?

i think its the outcome of people's preferences.

frederick william of brandenburg-prussia trained his son, frederick, to be a hardy soldier. but frederick disliked rifle shooting and horseback riding. unlike his father, he was interested in french literature. he enjoyed poetry and music and, like some others of the enlightenment, he scoffed at religion. his father thought him soft, frivolous and unmindful of his duties. and when frederick refused to put his signature on a right to succession, for a few moments his father strangled him.

b) the confederacy had to pay all union war expenses.

for hobos it was a very hard time most hid on the sides of the railroad tracks causing people to get bulls and get them off sometimes causing in fatal death they couldnt get people to give them money because the   people were also in need of money