What was the situation before the development before the creation of artificial cells

We discuss the experimental constraints to synthesize the most elementary cell-sized compartment that can self-reproduce using synthetic genetic information. The original idea was to program a phospholipid vesicle with DNA. Based on this idea, it was shown that in vitro gene expression could be carried out inside cell-sized synthetic vesicles.

there are two main types of historical sources: primary sources and secondary sources. a primary source is something that originates from the past. it can be a chronicle, a piece of pottery, or even a piece of glacial ice that gives us climate data about the levels of atmospheric carbon one thousand years ago.

answer; /// i believe the three where,tutankhamun,hatshepsut and , im not sure,but maybe (ramses the great)