How did the Columbian Exchange ' affect the American Indians and African slaves?

Economically the population decrease brought by the Colombian exchange caused a drastic labor shortage throughout America, which lead to the estbalishment of African Slavery on a big scale in the americas.

because its important to learn about other countries and how high tech they are compared to us. also its good to learn about other cultures and how ours differs and in common also we need to learn about companies that we still buy since they ship it here.