Why did European countries begin looking for trade routes that did not pass through Italy?

So they can avoid trouble that is throughout italy

Explanation:

sorry If this is wrong

you are very ugly bro

explanation:

yes based on alexanders actions he deserved the title of "the great". his empire covered about 3,000 miles and he was able to establish the empire over a 13 year period of time. he was able to conquer many different places. he also defeated the persians. he conquered egypt and developed a city and named it after himself.