In what year did colonists on the eastern coast of North America first take up arms against the British?

On the night of April 18, 1775, hundreds of British troops marched from Boston to nearby Concord in order to seize an arms cache. Well-known Silversmith Paul Revere and other riders sounded the alarm, and colonial militiamen began mobilizing to intercept the Redcoat column

Fine until slavery ya ya haha