Western and Central Europe: 740,000 adults and children living with H I V and 12,000 deaths due to H I V. Eastern Europe and Central Asia: 1.7 million with H I V and 84,000 deaths. East Asia: 750,000 with H I V and 43,000 deaths. South and Southeast Asia: 7.8 million with H I V and 90,000 deaths. Oceania (including Australia and New Zealand): 81,000 with H I V and 4,000 deaths. Middle East and North Africa: 460,000 with H I V and 36,000 deaths. Sub-Saharan Africa: 24.7 million with H I V and 2.1 million deaths. Which area of the world has the most people living with HIV/AIDS? the Middle East and North Africa Sub-Saharan Africa South and Southeast Asia Eastern Europe and Central Asia