The greatest problem facing the united states during the period of "manifest destiny" was

The answer is: whether slavery would expand across the United States,

Manifest destiny Refers to the view that United States was destined by Gods to conquer all the territories in the north american continent.

This view originated from the southern colonies in mid 1800s. At that time, people worried that this view could lead to military expansion on northern states and expand the practice of slavery to these areas.

in february 1787, congress decided that a convention should be convened to revise the articles of confederation, the nation’s first constitution. in may, 55 delegates came to philadelphia, and the constitutional convention began. debates erupted over representation in congress, over slavery, and over the new executive branch. the debates continued through four hot and muggy months. but eventually the delegates reached compromises, and on september 17, they produced the u.s. constitution, replacing the articles with the governing document that has functioned effectively for more than 200 years.