How would the proclamation of 1763 conflict with the concept of natural rights

The Royal Proclamation of 1763 was issued October 7, 1763, by King George III following Great Britain's acquisition of French territoryin North America after the end of the French and Indian War/Seven Years' War, which forbade all settlement west of a line drawn along the Appalachian Mountains.[1] It rendered worthless land grants given by the British government to Americans who fought for the crown against France. The Proclamation angered American colonists who wanted to continue their westward expansion into new farm lands and wanted to keep their control of local government. The Royal Proclamation continues to be of legal importance to First Nations in Canada. The 1763 proclamation line is similar to the Eastern Continental Divide's path running northwards from Georgia to the Pennsylvania–New York border, and north-eastwards past the drainage divide on the St. Lawrence Divide from there northwards through New England.