What problems did farmers face in the 1800s?

Farmers faced Native American raids, poor growing conditions, droughts, disease,
pay higher prices for transportation which caused less profit 

Well they didn't have machinery and not having machinery was a bit of a problem because not only they didn't have the modern machinery of today but they didn't have the equipment of revising food to check if they were giving out something that could cause sickness.

To be honest i thinks its between the first answer and the third answer

Good luck: )