In what ways were each of the major regions of the british colonies similar to one another, and in what ways were they different

The major similarities would be that all people that settle in those regions came with the hope to find new opportunities and lands.
The different would be the utilization of slave labors.
The middle and new England have few slave labors and utilizing scientific inventions for their production.
The southern colonies on the other hand, had a lot of slaves that made up around 1/3 of their population, while not utilizing scientific inventions.

The colony was represented by the house of burgesses