During natural selection, which organisms are most likely to survive as the environment changes?

For this case, we have by definition, natural selection is a phenomenon of evolution that can be understood as the differential reproduction of the genotypes of a given biological population.

As the environment undergoes changes, the organisms most likely to survive will be those that adapt to the environment and develop survival skills.

Example:

When antibiotics are ingested to eliminate a certain type of bacteria, although it is true that most die, a few develop resistance to the antibiotic, this is known as adaptation to the environment.

the organisms most likely to survive will be those that adapt to the environment and develop survival skills.