Biopsy is often used to distinguish cancerous from harmless tumors before resorting to surgery. Ridgway et al. (2004) investigated the ability of MIB-1 monoclonal antibodies, which detect rapidly proliferating cells with staining, to distinguish known breast tumor types from biopsies on a postoperative sample. The measurements given in the file 'AntibodyTumorScreening. csv' were taken to determine whether the BIB-1 index measured on biopsy is associated with tumor size. The MIB-1 index was measured double-blind on histological sections of tumor tissue by the number stained cells counted at a particular microscope magnification. Based on this information, which of the following options is most appropriate? 1. Use Spearman's rank-based correlation on the untransformed data
2. Use Pearson's correlation coefficient on the untransformed data
3. Use Pearson's correlation coefficient with only MIB-1 index log-transformed
4. Use Pearson's correlation coefficient with both tumor size and MIB-1 index log-transformed
5. Use Pearson's correlation coefficient with only tumor size log-transformed
tumorSize MIB1Index 10 1 13 39 15 7 20 154 20 141 20 26 21 41 23 1 25 7 25 24 26 67 30 1 30 27 35 1 35 35 42 40 37 45 2 47 1 70 23 130 93 130 32 19