Which method of data collection would be most appropriate: A study of the effects of new drug intended to treat Dementia.

Suppose you want to transform the graph of the function y=tan(x+pi/4)-1 into the graph of the function y=-tan(x+pi/2)+1 which transformations should you perform. a) reflect the graph of the first function across the x-axis, translate it pi/4 units to the left, and translate it 2 units up. b) reflect the graph of the first function across the x-axis, translate it pi/4 units to the right, and translate it 2 units up. c) reflect the graph of the first function across the line y = -1, translate it pi/4 units to the left, and translate it 2 units up. d) reflect the graph of the first function across the line y = -1, translate it pi/4 units to the right, and translate it 2 units up.