In gout, accumulation of urate crystals in subcutaneous tissues causes formation of white nodules known as ; precipitation of urate in the kidneys causes renal

The urate crystal has white nodules known as tophi. The precipitation of urate causes renal failure.

Explanation:

Gout may be defined as a condition of inflammatory arthritis due to the deposition of excess uric acid in the blood. Pain, swelling and tenderness are the common symptoms of gout.

Tophi are the white nodules of urate crystal that may get deposit under subcutaneous tissue due to the excess formation of uric acid in gout disease. Severe gout condition may also causes renal failure due to the precipitation of urate in the kidney in an individual.

Thus, the white nodules is tophi. Urate precipitation in kidney causes renal failure.

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