The important feature of the target cells that allows them to respond to hormones is the
a. proximity to the source of the hormone
b. type of nerve supply of the target cell.
c. type of nerve supply to the target cell.
d. presence of appropriate receptor molecules.
e. surface area of the target cell membrane.

D. Presence of appropriate receptor molecules.

Explanation:

Various hormones circulates over the entire body, they come in contact with almost every cell of the body but it usually affects the limited number of cells which are called as target cells. The target cell will respond to the hormone because it posses the receptor molecules for providing the desired action for the hormonal cell interaction.  

explanation:

1)drink water

2)try concentrating on what u r doing to distract urself from the headache and manipulate ur brain

3)go to sleep.its an easier yet time consuming way

4) massage ur temple and head