Medicine, 18.11.2020 19:10 sports1997

• Um menino de 7 anos, 30kg, receberá fenobarbital para tratamento de epilepsia. Calcule a dose de manutenção que produzirá concentração plasmática de 25mg/L. Sabe-se que o Cl de fenobarbital é maior em crianças = 2mL/kg/h. Dose de manutenção = CSS . CL. T 25mg/L x 2mL/Kg/h 50mg/Kg/h
F. S 0,9 x 0,95 0,855
Dose de manutenção = 58,47 mg/kg/h

Sabendo que o menino usará comprimidos que somam a dose de 120mg/dia, analise o impacto desta dose para a concentração plasmática.
2mL/Kg/h x 24h = 48mL/Kg/dia
CSS = F.(D/T) CSS = 0,9 (120mg/dia CSS = 2,25 mg/mL
Cl 48mL/Kg/dia

• Qual seria a faixa de dose que este paciente poderia receber sabendo que a faixa terapêutica do fenobarbital é 15-40mg/L?

Answers: 2

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• Um menino de 7 anos, 30kg, receberá fenobarbital para tratamento de epilepsia. Calcule a dose de m...

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