It’s a fill in the blank

this allows people to make the best decision or pursue the best option. when alternatives are weighed using their advantages and disadvantages, the option whose disadvantages outweigh the advantages (based on a qualitative or quantitative analysis) are shunned while those whose advantages outweigh their disadvantages are pursued.  

the skeletons of most mammals reach a certain size and then stop growing. however, many animals, including some mammals, keep growing throughout their lives. kangaroos, for example, just keep growing and growing until they die. also, the longer an animal lives the greater the chance it might catch some deadly disease.

+15-35=-20

going in opposite directions