Although most psychoactive substances interact with specific substances in the brain cells, the effects of are much more complex because several different neurotransmitter systems are affected.
a. opiates
b. tranquilizers
c. alcohol
d. marijuana

Alcohol

Explanation:

Alcohol has positive as well as negative effects on the healthy lifestyle of a person. People used it as a depressant. Alcohol slows down the activity of a person. The effect of alcohol depends on consumer capacity. Most of the people take it for enjoyment or loosen up the stress. When a person consumes alcohol more than capacity, it leads to the depressant. A person starts to lose control over things. More than capacity, if someone consuming the alcohol leads to the severe depressant condition. A person starts to feel vomiting, nausea, withdrawal symptoms, coma death, unconsciousness, etc. These all depend on the reaction of the person.

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the economic difference between the three colonial regions. shipbuilding, whaling, fishing, and trapping where also main factors to the economy. the southern regional colonies economy was based on sugarcane, rice, cotton, tobacco, and indigo.