This city was a major power in Mesopotamia for nearly 5000 years. A ur B Memphis C thames D Alexandria

A. Uruk

Explanation:

At one point in time (around 2900 BC), Uruk was regarded as the Largest City in the world. This city was located near Euphrates River, which made it easy for the agricultural sector in the city to flourish.  

The river also enable the people in the city to freely travel to distribute various types of goods to other territory. This made the city able to accumulate a lot of wealth. At the peak of its power, this city had around  80,000 population (which a lot for early societies in that era)

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